Collection: Fluorescence Detection Labeling Reagents (for Hydroxy Groups) [HPLC Derivatization Reagents]

Fluorescence Detection Labeling Reagents (for Hydroxy Groups) [HPLC Derivatization Reagents] — contains derivatization reagents that react selectively with hydroxyl groups to form fluorescent derivatives, so that target compounds can be detected with high sensitivity on a fluorescence instrument. This class is an important tool in HPLC analysis for compounds that do not fluoresce naturally.

Reagents such as NBD-COCl or DBD-Pro-COCl derivatives are used by chemical and pharmaceutical analysts to label hydroxyl groups before HPLC separation, including determination of enantiomeric excess (e.e.) for chiral compounds. These reagents are also used in quantitative analysis of sugars, alcohols, and metabolites that are difficult to detect directly.

Example products in this collection: TCI A0411 504-29-0 2-Aminopyridine, TCI D0005 605-65-2 Dansyl Chloride (10% in Acetone), TCI A5579 2705189-79-1 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl Chloride Hydrochloride [for HPLC Labeling], TCI D0656 605-65-2 Dansyl Chloride, TCI A5572 140164-85-8 NBD-COCl [=4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling], TCI A1657 446044-44-6 (1R,2R)-2-(Anthracene-2,3-dicarboximido)cyclohexanecarboxylic Acid, TCI A5567 159717-68-7 (S)-(-)-NBD-Pro-COCl [=(S)-(-)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination], TCI A5558 156153-43-4 DBD-COCl [=4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole] [for HPLC Labeling].

Pay attention to the optical purity of chiral reagents (R- or S-), the stability of acid chloride groups against moisture, and the suitability of the excitation-emission wavelengths with the detector being used. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under HPLC Derivatization Reagents, often used together in one laboratory workflow:

• Fluorescence Detection Labeling Reagents (for Amino Groups) [HPLC Derivatization Reagents]
• UV Detection Labeling Reagents (for Amino Groups) [HPLC Derivatization Reagents]
• Fluorescence Detection Labeling Reagents (for Carboxy Groups) [HPLC Derivatization Reagents]
• Fluorescence Detection Labeling Reagents (for Thiol Groups) [HPLC Derivatization Reagents]
• UV Detection Labeling Reagents (for Carboxyl Groups) [HPLC Derivatization Reagents]
• Fluorescence Detection Labeling Reagents (for Carbonyl Groups) [HPLC Derivatization Reagents]

Back to HPLC Derivatization Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.