Collection: UV Detection Labeling Reagents (for Amino Groups) [HPLC Derivatization Reagents]

UV Detection Labeling Reagents (for Amino Groups) [HPLC Derivatization Reagents] — includes labeling reagents such as isothiocyanates, acyl chlorides, and succinimidyl esters that react with both primary and secondary amino groups to form UV-detectable chromophoric derivatives. These reagents are a standard derivatization tool in HPLC analysis of compounds that are difficult to detect directly.

This class of reagents is used by analytical and biochemistry researchers to label amino acids, peptides, and amino sugars before separation and measurement by HPLC, such as in the phenyl isothiocyanate derivatization method for protein sequencing. Fluorinated dinitrophenyl derivatization reagents are also used specifically for optical purity (e.e.) determination in the stereochemical analysis of chiral compounds.

Product examples in this collection: TCI B0105 98-88-4 Benzoyl Chloride, TCI D1382 56512-49-3 Dabsyl Chloride [N-Protecting Agent for Peptides Research], TCI A5524 178065-30-0 Nalpha-(5-Fluoro-2,4-dinitrophenyl)-D-leucinamide [HPLC Labeling Reagent for e.e. Determination], TCI D1653 7612-98-8 4-(Dimethylamino)azobenzene 4'-Isothiocyanate, TCI A5523 178065-29-7 Nalpha-(5-Fluoro-2,4-dinitrophenyl)-L-leucinamide [HPLC Labeling Reagent for e.e. Determination], TCI D2259 95713-52-3 Nalpha-(5-Fluoro-2,4-dinitrophenyl)-L-alaninamide [HPLC Labeling Reagent for e.e. Determination], TCI A5522 68123-33-1 N-Succinimidyl 4-Nitrophenylacetate [for HPLC Labeling], TCI F0197 28920-43-6 9-Fluorenylmethyl Chloroformate [N-Protecting Agent for Peptides Research].

Pay attention to the reactivity match between the reagent and the target amino group, the chiral purity when used for e.e. determination, and the reagent's stability against humidity and light during storage. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other sibling categories under HPLC Derivatization Reagents, often used together in one laboratory workflow:

Back to HPLC Derivatization Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official distributor of TCI Japan in Indonesia — to check availability and direct lead time from Japan.

Related TCI catalogs (PDF)

15 products