Collection: Fluorescence Detection Labeling Reagents (for Carboxy Groups) [HPLC Derivatization Reagents]

Fluorescence Detection Labeling Reagents (for Carboxy Groups) [HPLC Derivatization Reagents] — includes fluorescent labeling reagents such as brominated acridine and benzoxadiazole derivatives designed to react selectively with carboxyl groups to form fluorescent derivatives. These reagents enable detection of compounds that do not naturally fluoresce strongly in chromatographic analysis.

Reagents in this category are used by analysts and researchers in analytical chemistry to derivatize carboxylic acids, fatty acids, or metabolites before HPLC separation, so that the resulting fluorescence signal increases detection sensitivity compared with conventional UV detection. Derivatives such as bromomethyl acridine or coumarin are widely used in fatty acid profiling and metabolomics studies.

Example products in this collection: TCI B1926 1556-34-9 9-(Bromomethyl)acridine [for HPLC Labeling], TCI M0760 26093-31-2 7-Amino-4-methylcoumarin [for HPLC Labeling], TCI A5576 254973-02-9 AABD-SH (=4-Acetamido-7-mercapto-2,1,3-benzoxadiazole) [for HPLC Labeling], TCI A0979 2747-04-8 7-Acetoxy-4-bromomethylcoumarin [for HPLC Labeling], TCI A5574 189373-41-9 DBD-ED [=4-(N,N-Dimethylaminosulfonyl)-7-(2-aminoethylamino)-2,1,3-benzoxadiazole] [for HPLC Labeling], TCI A5502 24463-19-2 9-Chloromethylanthracene [for HPLC Labeling], TCI A5573 221263-97-4 NBD-CO-Hz [=4-(N-Hydrazinocarbonylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling], TCI A5551 35231-44-8 Br-Mmc (=4-Bromomethyl-7-methoxycoumarin) [for HPLC Labeling].

Pay attention to reagent purity, light stability due to the photosensitive nature of the fluorophore groups, and the recommended derivatization reaction conditions (solvent, catalyst) for optimal labeling results. All products are original Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under HPLC Derivatization Reagents, often used together in a single laboratory workflow:

• Fluorescence Detection Labeling Reagents (for Amino Groups) [HPLC Derivatization Reagents]
• UV Detection Labeling Reagents (for Amino Groups) [HPLC Derivatization Reagents]
• Fluorescence Detection Labeling Reagents (for Hydroxy Groups) [HPLC Derivatization Reagents]
• Fluorescence Detection Labeling Reagents (for Thiol Groups) [HPLC Derivatization Reagents]
• UV Detection Labeling Reagents (for Carboxyl Groups) [HPLC Derivatization Reagents]
• Fluorescence Detection Labeling Reagents (for Carbonyl Groups) [HPLC Derivatization Reagents]

Back to HPLC Derivatization Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.