Collection: Glycosyl Donors [Glyco Building Blocks]

Glycosyl Donors [Glyco Building Blocks] — includes activated sugar compounds such as trichloroacetimidates, thioglycosides, and glycosyl fluorides equipped with acetyl or pivaloyl protecting groups, designed to react as sugar unit donors in the formation of glycosidic bonds. The reactivity of the leaving group at the anomeric position is the hallmark of this compound group.

Glycosyl Donors are used by carbohydrate synthesis researchers to form glycosidic bonds with sugar acceptors through chemical activation using promoters such as Lewis acids or heavy metals, yielding oligosaccharides and complex glycoconjugates. Thioglycoside- and trichloroacetimidate-based donors are widely used in iterative glycosylation to build branched glycan structures that resemble natural glycans in glycobiology research.

Example products in this collection: TCI T2811 13100-46-4 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, TCI G0225 604-68-2 Penta-O-acetyl-alpha-D-glucopyranose, TCI T2568 2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl Fluoride, TCI G0247 4163-60-4 Penta-O-acetyl-beta-D-galactopyranose, TCI T2567 174511-17-2 2,3,4,6-Tetra-O-acetyl-D-mannopyranosyl Fluoride, TCI I0328 367-93-1 Isopropyl 1-Thio-beta-D-galactopyranoside, TCI T2491 92052-29-4 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl 2,2,2-Trichloroacetimidate, TCI M1501 64550-71-6 Methyl 2,3,4,6-Tetra-O-acetyl-1-thio-alpha-D-mannopyranoside (contains ca. 5% beta-isomer).

Choose a donor based on the leaving group type (fluoride, imidate, or thio) that matches the available activation conditions, and pay attention to the alpha/beta isomer ratio and protecting group pattern for selective glycosylation results. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Glyco Building Blocks, often used together in a single laboratory workflow:

• Sugar Building Blocks by Target Oligosaccharides
• MP Glycosides [Glyco Building Blocks]
• pNP(para-Nitorophenyl) Glycoseides [Glyco Building Blocks]
• Glycosyl Azides, Aminoethyl Glycosides, Aminopropyl Glycosides [Glyco Building Blocks]

Back to Glyco Building Blocks. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — for stock availability checks and lead time directly from Japan.