Non-Heterocyclic Fluorinated Building Blocks — contains compounds with fluorine atoms on non-heterocyclic frameworks, such as trifluoromethyl, fluoroalkyl, and fluoroaryl groups attached to open carbon chains. This fluorine substitution alters the electronic properties, lipophilicity, and metabolic stability of compounds compared with their non-fluorinated analogues.
Non-Heterocyclic Fluorinated Building Blocks are used by synthetic chemists to introduce fluorine into target molecules through fluorination, trifluoromethylation, or coupling reactions using fluorinated reagents as starting materials. These building blocks are widely sought in medicinal chemistry and agrochemical research for their ability to direct the physicochemical properties of the final molecule.
Example products in this collection: TCI B1949 30071-93-3 3',5'-Bis(trifluoromethyl)acetophenone, TCI B5557 1637638-66-4 2-(tert-Butyldimethylsilyl)-1,3-phenylene Bis(trifluoromethanesulfonate), TCI B1751 401-95-6 3,5-Bis(trifluoromethyl)benzaldehyde, TCI B5645 79850-12-7 1,3-Bis(trifluoromethyl)cyclohexane (cis- and trans- mixture), TCI C2821 129825-11-2 4'-Chloro-3'-(trifluoromethyl)acetophenone, TCI B5646 433-18-1 1,4-Bis(trifluoromethyl)cyclohexane (cis- and trans- mixture), TCI A0377 393-11-3 5-Amino-2-nitrobenzotrifluoride, TCI B5688 345-24-4 1-Bromo-2,4-difluoro-5-nitrobenzene.
Pay attention to the position and number of fluorine substituents, the regioisomer purity, and the stability of compounds to moisture in reactive fluorinating reagents. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.
Other parallel categories under Fluorinated Building Blocks, often used together in a single laboratory workflow:
Back to Fluorinated Building Blocks. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.
