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Description
TCI C0380 Colchicine, CAS 64-86-8, is a plant-derived alkaloid widely used as a tubulin-binding inhibitor of microtubule polymerisation. By arresting dividing cells in metaphase, it is a standard tool for chromosome preparation, cell cycle studies, and antimitotic research, and is also applied in plant polyploidy induction work. This TCI grade is specified to contain a maximum of 5% ethyl acetate as residual solvent, which should be considered when preparing solutions. The material is highly toxic, intended strictly for trained laboratory research use, and is offered by AMI Scientific in 500 mg and 5 g packs.
