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Description
TCI 1-(Chloromethyl)-1H-benzotriazole (CAS 54187-96-1) combines a benzotriazole heterocycle with a reactive chloromethyl group at N-1. It is used to install a benzotriazolylmethyl unit onto nucleophiles, where the benzotriazole moiety acts as a removable synthetic auxiliary and leaving group. This strategy helps chemists control reactivity and regioselectivity in multi-step organic synthesis. AMI Scientific supplies 5 g and 25 g packs; keep tightly sealed away from moisture and follow the manufacturer's Safety Data Sheet.
Scientific References
Huang et al. (1999). ChemInform Abstract: Synthesis of 1‐Benzotriazolmethyl Phosphonate by Reaction of Sodium Phosphite with 1‐(Chloromethyl)benzotriazole.. ChemInformdoi:10.1002/chin.199926174
Huang et al. (1999). Synthesis of 1-benzotriazolmethyl Phosphonate by Reaction of Sodium Phosphite with 1-(chloromethyl)benzotriazole. Synthetic Communicationsdoi:10.1080/00397919908086036
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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