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Description
Dodecaethylene Glycol (DEG) is a chemical compound widely used in laboratory settings, particularly in the fields of chemical biology and protein modification. As a polyethylene glycol (PEG) derivative, DEG plays a crucial role in PEGylation processes, where it is used to modify biological molecules to enhance their stability, solubility, and functional activity. This compound is a key reagent in synthetic chemistry and biochemistry due to its versatile properties and compatibility with various experimental conditions. Its ability to act as a non-reactive solvent or additive makes it an essential component in many laboratory workflows.
DEG is preferred for its chemical stability, non-toxicity, and high water solubility. These characteristics ensure that it remains inert during chemical reactions, minimizing interference with the intended processes. Its high boiling point also allows it to be used in high-temperature applications without undergoing degradation. These properties make DEG a reliable and safe choice for both routine and specialized laboratory experiments. Its compatibility with a wide range of solvents and reagents further enhances its utility in diverse chemical and biochemical applications.
In Indonesian laboratories, DEG is commonly used as a raw material for the synthesis of complex compounds and as a helper in reactions requiring hydrophilic and highly soluble components. Its non-reactive nature and stability make it ideal for use as a solvent or additive in various experimental setups. DEG is also frequently employed in biotechnology and pharmaceutical research, supporting advancements in drug development and molecular modification. Its consistent performance and reliability make it a trusted material in both academic and industrial research environments.
Laboratory Applications
PEGylation of Proteins: DEG is ideal for modifying proteins to improve their solubility and stability, making it essential in biotechnology and pharmaceutical research.
Synthetic Organic Chemistry: Its high solubility and inert nature make it a valuable solvent in the synthesis of complex organic compounds.
Biochemical Reactions: DEG supports reactions requiring hydrophilic and highly soluble components, aiding in the preparation of biochemical reagents.
High-Temperature Reactions: The high boiling point of DEG allows it to be used in reactions that require elevated temperatures without degradation.
Laboratory Solvent: Its non-reactive and stable properties make it a suitable choice for use as a general-purpose solvent in various experimental setups.
Specifications
Brand: TCI
CAS number: 6790-09-6
Category: Chemistry > Chemical Biology > PEGylation
Pack sizes: Available in various sizes as per supplier specifications
Physical form: Liquid
Storage note: Store in a cool, dry place away from direct sunlight
Handling and Storage
DEG should be stored in a cool, dry place, away from direct sunlight and sources of heat. It is recommended to use airtight containers made of materials compatible with its chemical properties, such as glass or high-density polyethylene. Due to its high solubility in water, it is important to ensure proper containment to prevent accidental spills or contamination. As a non-toxic and stable compound, DEG requires minimal special handling, but standard laboratory safety protocols should be followed when working with it. Always ensure proper ventilation in the workspace and avoid inhalation of vapors during handling. Its inert nature reduces the risk of chemical interactions, making it relatively safe to handle under normal laboratory conditions.
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