Quinoline Hydrochloride TCI Q0013

Chemical Identity

CAS No.: 530-64-3
PubChem: CID 68264·SID 87575551
Formula: C9H8ClN
Molecular weight: 165.62 g/mol
Purity: >98.0%(T)(HPLC)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: quinoline;hydrochloride
SMILES: C1=CC=C2C(=C1)C=CC=N2.Cl
InChIKey: PSXRWZBTVAZNSF-UHFFFAOYSA-N

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Quinoline Hydrochloride TCI Q0013 is the salt formed when quinoline reacts with hydrochloric acid. In this compound, the nitrogen atom of the quinoline ring is protonated. The salt form is a more practical alternative to free quinoline, which is a liquid with a pungent odour. In the laboratory, quinoline hydrochloride serves as a source of the quinoline scaffold in synthesis. It is also used as a reagent in reactions that need an aromatic amine salt and as a model compound for studying the acid-base behaviour of nitrogen-containing heterocycles.

The main advantage of the hydrochloride form is that it is easier to handle. Because it is a solid, it can be weighed accurately, and its odour is much milder than that of the free base. The salt also tends to dissolve more readily in water and polar solvents, which makes aqueous solutions easier to prepare for analytical and biological experiments. When needed, free quinoline can be recovered by neutralising the salt with a base. This gives researchers flexibility when planning reaction sequences, since they can choose to work with either the salt or the free base at different stages of a synthetic route.

In Indonesia, quinoline hydrochloride is useful to organic chemistry, analytical chemistry, and pharmacy laboratories at universities and research institutions. Its solid form makes it practical to store, dispense, and weigh in teaching and research settings. Students can use it to study heterocyclic chemistry, while research groups can use it as a building block for quinoline-based compounds. As a TCI product listed under heterocyclic building blocks, it is a convenient option for laboratories that work regularly with nitrogen heterocycles.

Related TCI products

Heterocyclic synthesis: the compound supplies the quinoline scaffold for building more complex molecules, and its solid salt form makes accurate weighing and controlled addition easier.
Reactions requiring aromatic amine salts: the protonated quinoline nitrogen means it can be used directly as a reagent wherever a salt of an aromatic nitrogen base is needed.
Acid-base studies of nitrogen heterocycles: as the protonated form of quinoline, it is a suitable model for studying protonation, neutralisation, and related behaviour in heterocyclic bases.
Preparation of aqueous solutions: it tends to dissolve better in water and polar solvents than free quinoline, so aqueous solutions for analytical and biological work are easier to prepare.
Controlled recovery of free quinoline: neutralising the salt with a base gives back free quinoline, so researchers can generate the free base only when a reaction step needs it.

Brand	TCI (product code Q0013)
CAS number	530-64-3
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes	as listed in the product options on this page
Physical form	solid (hydrochloride salt of quinoline)
Storage	keep in a tightly closed container in a cool, dry, well-ventilated place; follow the manufacturer's label and SDS

Store quinoline hydrochloride in its original, tightly sealed container in a cool, dry, well-ventilated area, away from moisture, strong bases, and incompatible materials. Strong bases are a particular concern because they convert the salt back into free quinoline. Make sure containers are clearly labelled and closed again straight after use. Wear standard laboratory protective equipment when handling it, including gloves, safety glasses, and a lab coat. Weigh and transfer the solid in a fume hood or a well-ventilated area to avoid inhaling dust, and avoid contact with skin and eyes. Always read the supplier's Safety Data Sheet for detailed hazard information, and dispose of waste according to institutional and local regulations.

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