Collection: Difluoromethylation [Synthetic Reagents]
Difluoromethylation [Synthetic Reagents] — compiles silicon-based reagents and sulfonate esters bearing reactive difluoromethyl or trifluoromethyl groups, designed to transfer fluorocarbon units into target molecules via nucleophilic substitution or addition reactions.
Difluoromethylation [Synthetic Reagents] is used by synthetic chemists to introduce difluoromethyl or trifluoromethyl groups into aromatic and aliphatic compounds, either through reactions with fluoride-catalyzed silicon nucleophiles or through the formation of activated esters, as part of fluorination strategies in the development of organic molecules and intermediates.
Example products in this collection: TCI T4382 1885-46-7 Difluoromethyl Trifluoromethanesulfonate, TCI C0991 1895-39-2 Sodium Chlorodifluoroacetate, TCI T3022 120801-75-4 Trimethylsilyl Difluoro(fluorosulfonyl)acetate, TCI C1458 383-62-0 Ethyl Chlorodifluoroacetate, TCI T1570 81290-20-2 (Trifluoromethyl)trimethylsilane [Trifluoromethylating Reagent], TCI C1503 2834-23-3 Chlorodifluoroacetic Anhydride, TCI T1336 2923-18-4 Sodium Trifluoroacetate, TCI C1586 1514-87-0 Methyl Chlorodifluoroacetate.
Pay attention to the type of reagent group (trimethylsilyl, sulfonate ester, or fluorinated acetate derivative) and the stability of the reagent so that it suits the planned reaction conditions. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on each item's page.
Other categories at the same level under Fluorination Reagents [Synthetic Reagents], often used together in one laboratory workflow:
Back to Fluorination Reagents [Synthetic Reagents]. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.
