Collection: Olefination [C-C Bond Formation]

Olefination [C-C Bond Formation] — includes phosphonium and phosphonate reagents used to form carbon-carbon double bonds through olefination reactions such as Wittig and Horner-Wadsworth-Emmons, including phosphonium salts substituted with various functional groups and supporting reagents such as titanium(IV) chloride.

Olefination [C-C Bond Formation] is used in the synthesis of substituted alkenes at various stages of total synthesis of complex organic molecules, including natural products and active pharmaceutical ingredients. Synthetic chemists use phosphonium salts such as Wittig ylides to convert aldehyde or ketone groups into double bonds with certain geometric selectivity, while phosphonate reagents are used in Horner-Wadsworth-Emmons reactions for more controlled results.

Example products in this collection: TCI T4314 24720-64-7 2-(Triphenylphosphoranylidene)propanal, TCI B5730 13371-17-0 Butyltriphenylphosphonium Chloride, TCI T3904 136455-49-7 Octaethyl [Benzene-1,2,4,5-tetrayltetrakis(methylene)]tetrakis(phosphonate), TCI C1009 5293-84-5 (Chloromethyl)triphenylphosphonium Chloride, TCI T3238 7550-45-0 Titanium(IV) Chloride (ca 19% in Toluene, ca 10mol/L), TCI C1061 17814-85-6 4-(Carboxybutyl)triphenylphosphonium Bromide, TCI T2718 115754-62-6 Tributyl(1,3-dioxolan-2-ylmethyl)phosphonium Bromide, TCI C1286 7310-74-9 Cinnamyltriphenylphosphonium Bromide.

Reagent selection should consider the leaving group on the phosphonium, stability toward moisture, and the physical form of the reagent such as a solution in a specific solvent to facilitate handling in the laboratory. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on each item's page.

Other categories parallel under C-C Bond Formation [Synthetic Reagents], often used together in a single laboratory workflow:

• Cross-coupling Reaction using Transition Metal Catalysts [C-C Bond Formation]
• Weinreb Amides [C-C Bond Formation]
• C-C Bond Formation (Other) [Synthetic Reagents]
• Carbon Monoxide Surrogate Reagents [C-C Bond Formation]

Back to C-C Bond Formation [Synthetic Reagents]. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.