Collection: C-X(Non-Halogen) Bond Formation [Synthetic Reagents]

C-X(Non-Halogen) Bond Formation [Synthetic Reagents] — compiles synthetic reagents for forming non-halogen carbon-heteroatom bonds such as C-N, C-S, C-B, C-P, and C-C through amination, boration, cyanation, formylation, phosphorylation, and C-H activation. This group also includes reagents for azidation, guanidinylation, nitration, ethynylation, vinylation, and Mitsunobu reactions that expand functional groups on molecular frameworks.

C-X(Non-Halogen) Bond Formation reagents are widely used by synthetic organic chemistry and medicinal chemistry researchers to introduce amine, cyano, phosphonate, or vinyl groups into aromatic and aliphatic frameworks during compound library build-up. Reagents such as iodonium salts and phosphorodiamidites are often used in Mitsunobu, boration, or electrophilic functionalization reactions to assemble complex intermediates efficiently. This group also supports building block synthesis for functional materials and catalysis research.

Example products in this collection: TCI A0419 578-66-5 8-Aminoquinoline, TCI B5573 1868173-47-0 4-Biphenylyl(2,4,6-trimethoxyphenyl)iodonium Trifluoromethanesulfonate, TCI X0041 7647-01-0 Hydrogen Chloride - Methanol Reagent (5-10%) [for Esterification], TCI B5687 68014-21-1 tert-Butyl (Triphenylphosphoranylidene)carbamate, TCI X0039 7647-01-0 Hydrogen Chloride - Butanol Reagent (5-10%) [for Esterification] (1mL*10), TCI B5957 325773-62-4 2,2'-Bis[bis(3,5-dimethylphenyl)phosphino]-1,1'-biphenyl, TCI X0036 373-57-9 Boron Trifluoride - Methanol Reagent (10-20%) [for Esterification] (1mL*10), TCI B5997 108549-21-9 Benzyl N,N,N',N'-Tetraisopropylphosphorodiamidite.

Reagent selection in this category should consider purity, stability against moisture, and physical form such as ready-to-use solutions, crystalline powder, or single-use ampoule packaging according to reaction scale. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Synthetic Organic Reagents, often used together in one laboratory workflow:

• C-C Bond Formation [Synthetic Reagents]
• Protection, Deprotection, Derivatization
• Acids, Bases [Synthetic Reagents]
• Chelation/Complexation Compounds
• Phase Transfer Catalysts
• Coupling [Synthetic Reagents]

This collection is further divided into 12 more specific groups:

• C-H Bond Activation Reaction [Synthetic Reagents]
• Formylation [Synthetic Reagents]
• Phosphorylation [Synthetic Reagents]
• Mitsunobu Reaction [Synthetic Reagents]
• Vinylation [Synthetic Reagents]
• Amination [Synthetic Reagents]
• C-S Bond Formation [Synthetic Reagents]
• Ethynylation [Synthetic Reagents]
• Guanidinylation [Synthetic Reagents]
• Cyanation [Synthetic Reagents]
• Boration [Synthetic Reagents]
• C-X(Non-Halogen) Bond Formation (Other) [Synthetic Reagents]

Back to Synthetic Organic Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — authorized TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.