Collection: Solid Supported Synthesis

Solid Supported Synthesis — compiles functionalized polystyrene resins, silica gel, and scavenger reagents used as solid media for immobilizing molecules during synthesis reactions. This solid-phase-based approach simplifies separating the product from excess reagents without complicated chromatographic purification steps.

Solid Supported Synthesis is used by synthetic chemists in peptide and combinatorial synthesis to assemble molecules stepwise on cross-linked polystyrene resins, facilitating washing and harvesting of the product at each reaction cycle. Scavengers are used to capture excess reagents or by-products after the reaction is complete, while modified silica gel functions as a purification medium as well as a heterogeneous catalyst in parallel synthesis workflows in drug research laboratories.

Example products in this collection: TCI B2372 N-(4-Benzyloxytrityl)-N'-(2-nitrobenzenesulfonyl)-1,4-diaminobutane Resin cross-linked with 1% DVB (200-400mesh) (0.9-1.1mmol/g), TCI C1643 55844-94-5 Chloromethyl Polystyrene Resin cross-linked with 1% DVB (200-400mesh) (1.5-1.8mmol/g), TCI B2371 N-(4-Benzyloxytrityl)-N'-(2-nitrobenzenesulfonyl)-1,3-diaminopropane Resin cross-linked with 1% DVB (200-400mesh) (0.9-1.1mmol/g), TCI C1745 55844-94-5 Chloromethyl Polystyrene Resin cross-linked with 2% DVB (200-400mesh) (2.0-2.7mmol/g), TCI B2370 N-(4-Benzyloxytrityl)-N'-(2-nitrobenzenesulfonyl)-1,2-diaminoethane Resin cross-linked with 1% DVB (200-400mesh) (0.9-1.1mmol/g), TCI C1750 55844-94-5 Chloromethyl Polystyrene Resin cross-linked with 1% DVB (100-200mesh) (2.0-3.0mmol/g), TCI B2292 Bis(trifluoromethanesulfonyl)methyltetrafluorophenyl Polystyrene Resin cross-linked with 2% DVB (200-400mesh) (0.9-1.2mmol/g), TCI C1751 55844-94-5 Chloromethyl Polystyrene Resin cross-linked with 2% DVB (100-200mesh) (0.8-1.2mmol/g).

Pay attention to the degree of cross-linking of the resin, mesh particle size, and loading capacity in mmol per gram, as these determine binding efficiency and ease of handling at a given reaction scale. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Specialty Synthesis, often used together in one laboratory workflow:

• Ionic Liquids [Specialty Synthesis]
• Fluorous Synthesis
• Enzyme-Mediated Synthesis

This collection is further divided into 3 more specific groups:

• Polystyrene Resins [Solid Supported Synthesis]
• Scavengers [Solid Supported Synthesis]
• Silica Gel [Solid Supported Synthesis]

Back to Specialty Synthesis. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — for stock availability checks and lead time directly from Japan.