Collection: N-Heterocyclic Carbene (NHC) Ligands [Cross-coupling Reaction using Transition Metal Catalysts]

N-Heterocyclic Carbene (NHC) Ligands [Cross-coupling Reaction using Transition Metal Catalysts] — covers imidazolium and imidazolinium salts, CO2 carbene adducts, and stable free carbenes that serve as precursors to N-heterocyclic carbene (NHC) ligands for transition metal complexes. The diverse precursor forms make it easy to form metal-carbene complexes as needed for each reaction.

NHC ligands from this category are widely used in palladium- and nickel-catalyzed cross-coupling reactions such as Suzuki, Negishi, and Buchwald-Hartwig because of their strong electron-donating properties and thermal stability. Precursors such as imidazolinium salts and NHC-CO2 adducts are also used to form metal carbene complexes in situ without requiring a separate strong base.

Example products in this collection: TCI B3506 258278-28-3 1,3-Bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene, TCI B5603 917604-39-8 1,3-Bis(2,6-diisopropylphenyl)imidazolium-2-carboxylate, TCI B3465 244187-81-3 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene, TCI B6045 245679-18-9 1,3-Dimesityl-4,5-dihydro-1H-imidazol-3-ium Tetrafluoroborate, TCI B3158 173035-10-4 1,3-Bis(2,4,6-trimethylphenyl)imidazolinium Chloride, TCI B6281 1062158-66-0 3-[2,6-Bis(1-methylethyl)phenyl]-5,6,7,8-tetrahydro-4H-cycloheptathiazolium Perchlorate, TCI B3157 258278-25-0 1,3-Bis(2,6-diisopropylphenyl)imidazolinium Chloride, TCI C3429 1228185-09-8 2-Chloro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazolium Chloride.

Pay attention to the type of precursor (imidazolium/imidazolinium salt, CO2 adduct, or free carbene) and the aryl substituent on nitrogen (for example 2,6-diisopropylphenyl), as these determine the steric and electronic stability of the resulting ligand. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Cross-coupling Reaction using Transition Metal Catalysts [C-C Bond Formation], often used together in a single laboratory workflow:

• Phosphine Ligands [Cross-coupling Reaction using Transition Metal Catalysts]
• Palladium Catalysts [Cross-coupling Reaction using Transition Metal Catalysts]
• Nickel [Catalysis and Inorganic Chemistry]
• Nickel Catalysts [Cross-coupling Reaction using Transition Metal Catalysts]
• Copper Catalysts [Cross-coupling Reaction using Transition Metal Catalysts]
• Bases and Additives [Cross-coupling Reaction using Transition Metal Catalysts]

This collection is further divided into 3 more specific groups:

• Imidazolinium Salts, Cyclic Alkyl Amino Carbene (CAAC) Pecursors [Carbon-Donor Ligands]
• N-Heterocyclic Carbene (NHC)-CO2 Adducts and NHC-HCO3 Salts [Carbon-Donor Ligands]
• Stable Carbenes [Carbon-Donor Ligands]

Back to Cross-coupling Reaction using Transition Metal Catalysts [C-C Bond Formation]. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team, the official TCI Japan distributor in Indonesia, to check availability and direct lead time from Japan.