Collection: Phosphonium Salts, Uronium Salts, Formamidinium Salts [Coupling Reagents]

Phosphonium Salts, Uronium Salts, Formamidinium Salts [Coupling Reagents] — contains phosphonium, uronium, and formamidinium salts that function as activators of carboxylic groups in amide bond formation. The counter anions vary, ranging from tetrafluoroborate to hexafluorophosphate, which affect the solubility and reactivity of the reagents.

Phosphonium Salts, Uronium Salts, Formamidinium Salts [Coupling Reagents] are coupling reagents widely used in solid-phase and solution-phase peptide synthesis to form amide bonds efficiently and rapidly. Organic and pharmaceutical chemists use them in oligopeptide synthesis, bioactive conjugation, and the preparation of other amide compounds that require mild reaction conditions with minimal epimerization.

Example products in this collection: TCI T3569 255825-38-8 N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Tetrafluoroborate, TCI C1379 135540-11-3 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium Hexafluorophosphate, TCI T2929 265651-18-1 N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Hexafluorophosphate, TCI C1408 37091-73-9 2-Chloro-1,3-dimethylimidazolinium Chloride, TCI T2821 212333-72-7 N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate, TCI C1639 37091-73-9 2-Chloro-1,3-dimethylimidazolinium Chloride (ca. 25% in Dichloromethane), TCI T2224 105832-38-0 N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate, TCI C1651 101385-69-7 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate.

Please note the anion type (tetrafluoroborate or hexafluorophosphate), purity, and storage stability, as some coupling reagents are hygroscopic and sensitive to moisture, so they need to be stored in airtight containers. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on each item's page.

Other categories parallel under Coupling [Synthetic Reagents], often used together in a single laboratory workflow:

• Peptide Coupling Agents
• Active Esters, Additives [Coupling Reagents]
• Coupling Reagents (Other)
• Triflate Formation [Coupling Reagents]
• Carbodiimides [Coupling Reagents]
• Phosgene Derivatives [Coupling Reagents]

Back to Coupling [Synthetic Reagents]. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.