Collection: PEGylation

PEGylation — contains a range of polyethylene glycol (PEG) and oligoethylene glycol in monofunctional, homobifunctional, heterobifunctional, and mPEG forms, up to discrete PEG oligomers with defined chain lengths. These molecules act as hydrophilic linkers or spacers that connect two different functional groups on a conjugate.

PEGylation is used in bioconjugation chemistry to attach biomolecules, ligands, or tracer tags such as biotin through reactive groups such as amines, carboxylates, azides, or maleimides at the end of the PEG chain. Click chemistry and protein chemistry researchers use tetrazine-PEG derivatives and bifunctional PEG to build conjugates with adjustable spacing and solubility.

Example products in this collection: TCI T4298 2-[4-(1,2,4,5-Tetrazin-3-yl)phenyl]-N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]acetamide Hydrochloride, TCI B5587 186020-66-6 tert-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate, TCI T4280 Tetrazine-amido-PEG3-Biotin, TCI B5665 756525-91-4 (Boc-amino)-PEG4-carboxylic Acid, TCI T4279 2-[4-(1,2,4,5-Tetrazin-3-yl)phenyl]-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]acetamide, TCI B5668 86099-06-1 1,11-Bis(maleimido)-3,6,9-trioxaundecane, TCI T4277 2-[4-(1,2,4,5-Tetrazin-3-yl)phenyl]-N-[2-[2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy]ethyl]acetamide, TCI B5900 581065-95-4 tert-Butyl 1-Amino-3,6,9,12-tetraoxapentadecan-15-oate.

Match the type and position of the end-group functional groups to the intended reaction pair, and pay attention to the PEG chain length (number of ethylene glycol units), which affects the spacing and hydrophilic properties of the final conjugate. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each product's page.

Other categories at the same level under Chemical Biology, often used together in a single laboratory workflow:

This collection is further divided into 5 more specific groups:

Back to Chemical Biology. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.

58 products